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AboutTALZENNA MoATalzenna MoAgBRCA testingIdentifying patientsGuidelinesStudy designStudy designBaseline characteristicsEfficacy & SafetyTALZENNA efficacyPrimary endpoint & subgroup analysisSecondary endpoints: ORRSecondary endpoint: OSExploratory endpoints: DoR & TTRTALZENNA safetySafety and tolerabillityAdverse eventsPatient-reported outcomes with TALZENNAPatient-reported outcomesGHS/QoLBreast symptomsDosingDosingDose recommendation and special populationsDose modifications/managementPatient ProfilesPrescribing InformationSupport & ResourcesSupport & ResourcesMaterialsElevatePersonalising Breast Cancer TreatmentUnderstanding and Optimising PARP Inhibitors for mBCPARP Inhibitors in mBC: the role of Real World Evidence
Monitoring and managing patients on TALZENNA® 

Complete blood count should be obtained prior to starting TALZENNA® therapy and monitored monthly and as clinically indicated1

Dose modifications and management1
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Type of Adverse Reactions  Adverse Reactions Withhold TALZENNA Until Levels Resolve to  Resume TALZENNA
Haematologic Hemoglobin
<8 g/dL		 ≥9 g/dL Resume TALZENNA at a reduced dose
Platelet count <50,000/μL ≥75,000/μL
Neutrophil count <1,000/μL ≥1,500/μL
Nonhaematologic Grade 3 or Grade 4 ≤ Grade 1 Consider resuming TALZENNA at a reduced dose or discontinue 
AE=adverse event; PFS=progression-free survival. Explore more Patient profiles
Reference:TALZENNA® Summary of Product Characteristics. 

Legal Category: S1A 
Further information is available upon request

PP-TAL-IRL-0105 May 2024
Dosing Significantly longer PFS 

Superior to chemotherapy in delaying disease progression1

See the dataLoading Manageable safety profile

AEs were manageable with a low discontinuation rate1

Review safetyLoading
TALZENNA Summary of Product Characteristics Product CharacteristicsLoading

Adverse events should be reported. Report an adverse event to your national reporting system (HPRA Pharmacovigilance)
 

Adverse events should also be reported to Pfizer Medical Information on 1800 633 363

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PP-UNP-IRL-0832. October 2024
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PP-UNP-IRL-0832. October 2024