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TALZENNA® is indicated as monotherapy for the treatment of adult patients with germline BRCA1/2-mutations, who have HER2-negative locally advanced or metastatic breast cancer. Patients should have been previously treated with an anthracycline and/or taxane in the (neo)adjuvant, locally advanced or metastatic setting unless patients were not suitable for these treatments. Patients with hormone receptor (HR)-positive breast cancer should have been treated with a prior endocrine-based therapy, or be considered unsuitable for endocrine-based therapy.1
Please see full Prescribing Information and Patient Information.
TALZENNA® significantly prolonged median progression-free survival (PFS) vs chemotherapy: 8.6 vs 5.6 months (HR=0.54 [95% CI: 0.41-0.71]; P<0.0001)1
Significant improvements in GHS/QoL and breast symptoms2
AEs were manageable with a low discontinuation rate1
One dose once a day with or without food1
Legal Category: S1A
Further information is available upon request
Adverse events should be reported. Report an adverse event to your national reporting system (HPRA Pharmacovigilance)
Adverse events should also be reported to Pfizer Medical Information on 1800 633 363
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PP-UNP-IRL-0832. October 2024