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AboutTherapeutic IndicationsRheumatoid arthritisJuvenile idiopathic arthritisPsoriatic arthritisAxial spondyloarthritisPlaque psoriasis & Paediatric plaque psoriasisMechanism of actionMechanism of actionDosingDosingRheumatoid arthritis, psoriatic arthritis & axial spondyloarthritisJuvenile idiopathic arthritisPlaque psoriasisPaediatric plaque psoriasisAdministration & storageAdministrationMYCLIC®StorageEfficacy & SafetyEfficacy & SafetyRheumatoid arthritisAxial spondyloarthritisPsoriatic arthritisPlaque psoriasisJuvenile idiopathic arthritisSupport & ResourcesMaterials
DosingJuvenile idiopathic arthritis

    Patients treated with Enbrel should be given the Patient Card.

    The recommended dose of Enbrel for JIA patients is weight-based:1

  • 0.4mg/kg (up to a maximum of 25mg per dose) given as a subcutaneous injection twice weekly at an interval of 3-4 days between doses,or
  • 0.8 mg/kg (up to a maximum of 50 mg per dose) given once weekly
  • No formal clinical trials have been conducted in children aged 2 to 3 years. However, limited safety data from a patient registry suggest that the safety profile in children from 2 to 3 years of age is similar to that seen in adults and children aged 4 years and older, when dosed every week with 0.8 mg/kg subcutaneously
  • There is generally no applicable use of Enbrel in children aged below 2 years in the indication juvenile idiopathic arthritis.

Discontinuation of treatment should be considered in JIA patients who show no response after 4 months. The 10 mg vial strength may be more appropriate for children below the weight of 25 kg1

Dosing options adapted from Enbrel Summary of Product Characteristics1JIA: Juvenile idiopathic arthritis.Explore more Efficacy & Safety

Learn more about the efficacy and safety of Enbrel in JIA

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Pfizer has resources available to support you and your Enbrel patients

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PP-ENB-IRL-0270 May 2023

Adverse events should be reported. Report an adverse event to your national reporting system (HPRA Pharmacovigilance)
 

Adverse events should also be reported to Pfizer Medical Information on 1800 633 363

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